interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE FABT IN COMPLEX WITH DNA
(Fatty acid biosynthesis transcriptional regulator)
referenceChen et al. 'Febs 593 2730 2019
sourceStreptococcus pneumoniae
experimentX-ray (resolution=2.20, R-factor=0.189)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family; Penicillinase repressor 143;
multimeric complexes6jbx_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTLTTTR

Estimated binding specificities ?

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# IC=6.547 IC/col=0.727 n_of_columns=9 specificity:   
A |   0   8  24  68  73   0  24  96   0
C |   0  81  24   7   7  14  24   0   0
G |   0   0  24  14   7   7  24   0   0
T |  96   7  24   7   9  75  24   0  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----DCLT--AGTTRGRG--RA   L                 +-----------------5h3r_A    
                                 +-----------1 
  ----ST----TC--QGRG----       +-2           +-----------------7b24_C    
                               ! ! 
  --STSTQAQGSTSART--KT--   L --3 +-----------------------------5trd_B    
                               ! 
  RT------TCTGYTRT------       +-----------------------------7vpz_N    
                             

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updated Tue Dec 19 13:18:56 2023