6i1l_D : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF FNCAS12A IN COMPLEX WITH A CRRNA GUIDE AND SSDNA TARGET (CRISPR-associated endonuclease Cas12a)
reference	Swarts et al. 'Mol. 73 589 2019
source	Francisella tularensis subsp. novicida (strain U112) / Francisella tularensis subsp. novicida (strain U112)
experiment	X-ray (resolution=2.98, R-factor=0.207)
reference complex	6gtc_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6i1l_D interface=14,185,289,296,302,305,306,309,397,400,401,404,410,567,568,867,949, asiyqefvnkyslSktlrfelipqgktlenikarglilddekrakdykkakqiidkyhqffieeilssvcisedllqnysdvyfklkksdddnlqkdfksakdtikkqiseyikdsekfknlfnqnlidakkgqesdlilwlkqskdngielfkansditdidealeiiksfkgwttyfkgfheNrknvyssndiptsiiyrivddnlpkflenkakyeslkdkapeainyeqikkdlaeeltfdidyktsevnqrvfsldevfeianfnnylnqsgitkfntiiggkFvngentKrkginEyiNLysQqindktlkkykmsvlfkqilsdtesksfvidkleddsdvvttmqsfyeqiaafktveeksiketlsllfddlkaqkldlskiyfkndKslTDlsQqvfddYsvigtavleyitqqiapiakktekakylsletiklaleefnkhrdidkqcrfeeilanfaaipmifdeiaqnkdnlaqisikyqnqgkkdllqasaeddvkaikdlldqtnnllhklkifhisqsenildkdehfylvfeecyfelanivplynkiRNyitqkpysdekfklnfenstlangwdknkepdntailfikddkyylgvmnkknnkifddkaikenkgegykkivykllpgankmlpkvffsaksikfynpsedilrirnhsthtkngspqkgyekfefniedcrkfidfykqsiskhpewkdfgfrfsdtqrynsidefyrevenqgykltfenisesyidsvvnqgklylfqiynkdfsayskgrpnlhtlywkalfdernlqdvvyklngeaelfyrkqsipkkithpakeaianknkdnpkkesvfeydlikdkrftedkfffhcPitinfkssgankfndeinlllkekandvhilsidrgerhlayytlvdgkgniikqdtfniigmktnyhdklaaiekdrdsaRkdwkkinnikemkegylsqvvheiaklvieynaivvfqdlfkvekqvyqklekmlieklnylvfkdnefdktggvlrayqltapfetfkkmgkqtgiiyyvpagftskicpvtgfvnqlypkyesvsksqeffskfdkicynldkgyfefsfdyknfgdkaakgkwtiasfgsrlitrevyptkelekllkdysieyghgecikaaicgesdkkffakltsvlntilqmrnsktdylispvadvngnffdsrqapknmpqdadangayhiglkglmllgriknnqklnlvikneeyfefvqnrnn
interface signature	SNFKENLQKTDQYRNPR

Estimated binding specificities ?

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# IC=10.728 IC/col=0.536 n_of_columns=20

specificity:

A |  96   0  24   0  93  90  13  24  90  24   4  24  24  24  24  24  65  10  24   0
C |   0   0  24   0   0   2  10  24   2  24  88  24  24  24  24  24   8  15  24   0
G |   0   0  24  96   0   2  10  24   2  24   2  24  24  24  24  24  13  10  24   0
T |   0  96  24   0   3   2  63  24   2  24   2  24  24  24  24  24  10  61  24  96

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updated Mon Dec 18 15:28:26 2023