Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE FNCAS12A IN COMPLEX WITH A CRRNA GUIDE AND A DSDNA TARGET
(CRISPR-associated endonuclease Cas12a)
referenceSwarts et al. 'Mol. 73 589 2019
sourceFrancisella tularensis subsp. novicida (strain U112) / Francisella tularensis subsp. novicida (strain U112)
experimentX-ray (resolution=2.65, R-factor=0.249)
reference complex6gtc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=6.906 IC/col=0.432 n_of_columns=16 specificity:   
A |   7  21  14  96  12   0   9  24  24  24  24  21  24  24   0  96
C |   7  23  14   0  12  96  11  24  24  24  24  21  24  24  96   0
G |   8  21  14   0  12   0   9  24  24  24  24  21  24  24   0   0
T |  74  31  54   0  60   0  67  24  24  24  24  33  24  24   0   0
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updated Mon Dec 18 15:28:08 2023