6eo7_H : 3D-footprint complex

structure name	X-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN ALPHA-THROMBIN AND MODIFIED 15-MER DNA APTAMER CONTAINING 5-(3-(ACETAMIDE-N-YL)-1- PROPEN-1-YL)-2'-DEOXYURIDINE RESIDUE (PROTHROMBIN)
reference	Dolot et al. 'Nucleic 46 4819 2018
source	HOMO SAPIENS
experiment	X-ray (resolution=2.24, R-factor=0.163)
structural superfamily	Trypsin-like serine proteases;
sequence family	Trypsin;
multimeric complexes	1hap_HL 1hut_HL 4dih_HL 4dii_HL 4lz4_CD 6evv_HL 6gn7_HL 7zkl_HL
reference complex	6z8v_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6eo7_H interface=9,66,70,71,72,73,75,78, ivegsdaeIgmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendllvrigkHsrtRYERnIekIsmlekiyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge
interface signature	IHRYERII

Estimated binding specificities ?

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# IC=8.185 IC/col=0.682 n_of_columns=12

specificity:

A |  14   0   0  24  24  24  24  24   0   0   0   0
C |  14   0   0  24  24  24  24  24   0   0   0   0
G |  52   0  96  24  24  24  24  24  96   0   0  96
T |  16  96   0  24  24  24  24  24   0  96  96   0

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updated Mon Dec 18 15:00:07 2023