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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


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updated Mon Dec 18 14:33:18 2023
structure nameLYSYL-ADENYLATE FORM OF HUMAN LIGIV CATALYTIC DOMAIN WITH BOUND DNA SUBSTRATE IN OPEN CONFORMATION
(DNA ligase 4)
referenceSchellenberg et al. 'Nat 9 2642 2018
sourceHomo sapiens
experimentX-ray (resolution=3.25, R-factor=0.266)
structural superfamilyDNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;ATP-dependent DNA ligase DNA-binding domain;
sequence familyATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal r; DNA ligase N terminus 260; mRNA capping enzyme, catalytic domain 577;
reference complex6bkg_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence