interface graph thumbnail
legend  pdf

structure nameHUMAN PIT-1 AND 4XCATT DNA COMPLEX
(Pituitary-specific positive transcription factor 1)
referenceAgarwal et al. 'Nucleic 46 929 2018
sourceHomo sapiens
experimentX-ray (resolution=3.15, R-factor=0.233)
structural superfamilylambda repressor-like DNA-binding domains;Homeodomain-like;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes1au7_AB 5wc9_AB 5wc9_EF
reference complex1au7_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSQTCRRVNQ

Estimated binding specificities ?

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# IC=6.234 IC/col=1.039 n_of_columns=6 specificity:   
A |  96   0   0  96  96  19
C |   0   0   0   0   0  19
G |   0   0  77   0   0  20
T |   0  96  19   0   0  38
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updated Mon Dec 18 13:50:03 2023