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structure namePIT-1 MUTANT/DNA COMPLEX
(PROTEIN PIT-1)
referenceLeon-Del-Rio et al. 'Genes 11 198 1997
sourceRattus norvegicus
experimentX-ray (resolution=2.30, R-factor=?)
structural superfamilylambda repressor-like DNA-binding domains;Homeodomain-like;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes1au7_AB 5wc9_AB 5wc9_EF
redundant complexes5wc9_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSQTCRLNRRVCNQR

Estimated binding specificities ?

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# IC=11.576 IC/col=1.052 n_of_columns=11 specificity:   
A |   0   0   6  96   0  96   6  63   0  68   0
C |   0   0   6   0   0   0   6   0  96   0   0
G |   0  96  13   0   0   0   9  13   0  22   0
T |  96   0  71   0  96   0  75  20   0   6  96
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PIT-1
TATNCATPubMed1au7_A(2.52e-06), 1au7_AB(7.60e-06), 5wc9_AB(2.03e-03), ... (total=4)
TATAAPubMed1au7_A(5.59e-03), 1au7_AB(1.00e-02)
AATNCATPubMed1au7_A(1.13e-03), 1au7_AB(2.53e-03), 5wc9_AB(2.03e-03), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  ----------RA--------ITQTNAMG----   L                                             +5zjt_E    
                                                                    +--------------1 
  ----------RT--------NT--NAIARG--   L                              !              +1b72_B    
                                                                    ! 
  ----------RA------KGSAQA--------   L                   +----------5              +6j5b_C    
                                                         !          !      +-------2 
  --------RCRT--------NT--NAITRG--                       !          !      !       +5zjt_B    
                                                         !          +------4 
  --------------------IA--NA------                   +---6                 !      +4qtr_D    
                                                     !   !                 +------3 
  ----------RT--------ITQCNAACRG--   L               !   !                        +6a8r_A    
                                                   +-7   ! 
  ----------RTSTVC--KGDCRG--------   L             ! !   +-------------------------1w0t_A    
                                                 +-8 ! 
  ----------RT------KTIAQCNA----RT   L           ! ! +-----------------------------1ig7_A    
                                               +-9 ! 
  ----------RT--------IAKGNA------   L         ! ! +-----------------------------2hdd_A    
                                            +-10 ! 
  ----------RT--------NT--NA--RG--   L      !  ! +-----------------------------1b8i_B    
                                         +-11  !  
  --------------------NCITNARGRG--   L   !  !  +-----------------------------6fqq_E    
                                       -12  !  
  ----------RT--RTQT--ITQANAVTKT--   L   !  +-----------------------------2ld5_A    
                                         !  
  NTQASAHT--RT------YCNAATNAKG----   L   +-----------------------------1ic8_B    
                                       

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updated Tue Dec 19 05:25:12 2023