interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN EXONUCLEASE 1 EXO1 (D225A) IN COMPLEX WITH 5' RECESSED-END DNA (RVII)
(Exonuclease 1)
referenceBeese et al. 'Proc. 114 6010 2017
sourceHomo sapiens
experimentX-ray (resolution=2.75, R-factor=0.221)
structural superfamilyPIN domain-like;5' to 3' exonuclease, C-terminal subdomain;
sequence familyXPG Iregion; XPG Nterminal domain;
reference complex5v07_Z
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQHKIRRT

Estimated binding specificities ?

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# IC=2.635 IC/col=0.439 n_of_columns=6 specificity:   
A |  67   9  24  24   9   0
C |   9   9  24  24   9   0
G |   9  67  24  24  67   0
T |  11  11  24  24  11  96
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updated Mon Dec 18 13:41:09 2023