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structure nameCRYSTAL STRUCTURE OF HUMAN EXONUCLEASE 1 EXO1 (D173A) IN COMPLEX WITH 5' RECESSED-END DNA (RV)
(Exonuclease 1)
referenceBeese et al. 'Proc. 114 6010 2017
sourceHomo sapiens
experimentX-ray (resolution=2.15, R-factor=0.179)
structural superfamilyPIN domain-like;5' to 3' exonuclease, C-terminal subdomain;
sequence familyXPG Iregion; XPG Nterminal domain;
redundant complexes3qe9_Z 3qea_Z 3qeb_Z 5uzv_Z 5v04_Z 5v05_Z 5v06_Z 5v08_Z 5v09_Z 5v0a_Z 5v0b_Z 5v0c_Z 5v0d_Z 5v0e_Z 7mxq_Z 7mxr_Z 7mxs_Z 7mxt_Z 7mxu_Z 7mxv_Z 7mxw_Z 7mxx_Z
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  CTHTKAIA------------RTRCRG              +---------5v07_Z    
                                   +------2 
  ----------TG--LGKGSG------       !      !  +------1rxw_A    
                                 --3      +--1 
  --------AGVG--QC--MC------       !         +------5zoe_A    
                                   ! 
  ITYTQT------KT------------       +----------------4q0w_A    
                                 

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updated Tue Dec 19 11:26:17 2023