interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THYMINE DNA GLYCOSYLASE BOUND TO SUBSTRATE ANALOG 2'-F-5- FORMYL-DC
(GT mismatch-specific thymine DNA glycosylase)
referencePozharski et al. Biochemistry 55 6205 2016
sourceHomo sapiens
experimentX-ray (resolution=2.20, R-factor=0.182)
structural superfamilyUracil-DNA glycosylase-like;
sequence familyUracil DNA glycosylase superfamily;
multimeric complexes2rba_AB 3ufj_AB 3uo7_AB 3uob_AB
reference complex4z47_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSKKARCAQ

Estimated binding specificities ?

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# IC=3.143 IC/col=0.786 n_of_columns=4 specificity:   
A |  15  85   0   7
C |  17   3  96   4
G |  15   3   0   4
T |  49   5   0  81
scan!

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updated Mon Dec 18 13:32:26 2023