Estimated binding specificities ?

structure nameHUMAN THROMBIN SANDWICHED BETWEEN TWO DNA APTAMERS: HD22 AND HD1- DELTAT3
(THROMBIN HEAVY CHAIN)
referenceRusso Krauss et al.
sourceHOMO SAPIENS
experimentX-ray (resolution=2.95, R-factor=0.158)
structural superfamilyTrypsin-like serine proteases;
sequence familyTrypsin;
multimeric complexes1hap_HL 1hut_HL 4dih_HL 4dii_HL 4lz4_CD 6evv_HL 6gn7_HL 7zkl_HL
reference complex6z8v_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=10.441 IC/col=0.614 n_of_columns=17 specificity:   
A |  16   0  31  24  24  24  24  24  24  24   0   0   0   0   0   2   0
C |  16   0  21  24  24  24  24  24  24  24   0   0   0   0   0   4   0
G |  45   0  23  24  24  24  24  24  24  24   0   0  96  96  96  88   0
T |  19  96  21  24  24  24  24  24  24  24  96  96   0   0   0   2  96
scan!

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updated Mon Dec 18 12:39:13 2023