5eix_BJ : 3D-footprint complex

structure name	QUINOLONE-STABILIZED CLEAVAGE COMPLEX OF TOPOISOMERASE IV FROM KLEBSIELLA PNEUMONIAE
reference	Sanderson et al. 'Acta 72 488 2016
source	KLEBSIELLA PNEUMONIAE
experiment	X-ray (resolution=3.35, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	6waa_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5eix_B interface=45,243,302,303,338,391,545, gkladctaqdlnrtelflvegdsaggsakqardreyqaimplkgKilntwevssdevlasqevhdisvaigidpdsddlsqlrygkiciladadsdglhiatllcalfvrhfrtlvkeghvyvalpplyridlgkevyyalteeektgvleqlkrkkgkpnvqrfkglgemnpmqlrettldpntrrlvqlvisdedeqqttaimdmllakkrsedrrnwlqekgmaerlalheftenaylnYsmyvimdralpfigdglkpvqrrivyamselglnasakfkksartvgdvlgkyhphgdSAcyeamvlmaqpfsyryplgdgqgnwgapksfaamRytesrlskyaelllselgqgtvdwvpnfdgtlqepkmlparlpnillngttgIavgmatdipphnlrevakaaitlieqpkttldelldivqgpdfpteaeiitsraeirkiyqngrgsvrmravwskedgavvitalphqvsgakvleqiaaqmrnkklpmvddlrdesdhenptrlvivprsnrvdmeqvmnhlfattdleksyRinlnmigldgrpavknlleilsewlvfrrdtvrrrlnhrlekvlkrlhilegllvaflnidevieiirtedepkpalmsrfgisetqaeailelklrhlakleemkirgeqselekerdqlqailaserkmnnllkkelqadadafgddrrsplhe > 5eix_J interface=45,289,324,377,524, gkladctaqdlnrtelflvegdsaggsakqardreyqaimplkgKilntwevssdevlasqevhdisvaigidpdsddlsqlrygkiciladadsdglhiatllcalfvrhfrtlvkeghvyvalpplyrivyyalteeektgvleqlkrqrfkglgemnpmqlrettldpntrrlvqlvisdedeqqttaimdmllakkrsedrrnwlqekgerlalheftenaylnysmyvimdralpfigdglkpvqrrivyamselglnasakfkksartvgdvlgkyhphgdsAcyeamvlmaqpfsyryplgdgqgnwgapksfaamRytesrlskyaelllselgqgtvdwvpnfdgtlqepkmlparlpnillngttgIavgmatdipphnlrevakaaitlieqpkttldelldivqgpdfpteaeiitsraeirkiyqngrgsvrmravwsitalphqvsgakvleqiaaqmrnkklpmvddlrdesdhenptrlvivprsnrvdmeqvmnhlfattdleksyRinlnmigldgrpavknlleilsewlvfrrdtvrrrlnhrlekvlkrlhilegllvaflnidevieiirtedepkpalmsrfgisetqaeailelklrhlakleemkirgeqselekerdqlqailaserkmnnllkkelqadadafgddrrsplh
interface signature	KYSARIR/KARIR

Estimated binding specificities ?

readout + contact

# IC=7.696 IC/col=0.550 n_of_columns=14

specificity:

A |   0   0  24  61  24   9  24  24  15  24   0  24   0  96
C |   0   0  24  13  24   6  24  24  68  24   8  24  96   0
G |   0  96  24   6  24  75  24  24   0  24   6  24   0   0
T |  96   0  24  16  24   6  24  24  13  24  82  24   0   0

scan!

home
updated Sat Dec 16 00:57:21 2023