5e67_A : 3D-footprint complex

structure name	K103A/K262A DOUBLE MUTANT OF I-SMAMI (I-SmaMI LAGLIDADG meganuclease)
reference	Stoddard et al. J.Mol.Biol. 428 206 2016
source	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) / Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
experiment	X-ray (resolution=2.20, R-factor=0.183)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
redundant complexes	4z1z 4z20 5e5o
reference complex	4lox_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5e67_A interface=16,18,20,22,26,27,32,34,38,40,63,65,69,71,73,75,177,179,181,185,186,191,193,197,199,221,223,225,228,230,234, klnpwavvgfidaegSfMvRvRknsKYktgwLvVaifSvTvdkkdlflleslktffgglgsiKkSgnsTfSyRiEsseqltkiilpffdkyslitealgdyllfkkvlelmgtkehltqrglekivslkasinkglseelqaafpqcvptprpeinnknipdpfwlagfvsgdgsfKsIlKkseSIkvgfQsIlvfQiTqhardvklmeslisylgcgfiEkDsRgpWlYytvTnfsdiqgkiipffhqykiigsaygdyqdwckialimqnknhltpeglneiralkggmnkg
interface signature	SMRRKYLVSTKSTSREKIKSIQIQTEDRWYT

Estimated binding specificities ?

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# IC=20.825 IC/col=0.992 n_of_columns=21

specificity:

A |   0  75   0   0   0   1   0   0  75  24  24  24   6   0  96   0   0   0   0   0  78
C |   0   9   0  96  96   6  96  96   6  24  24  24  13  96   0   0   0   0   0   0   6
G |   0   6   0   0   0   0   0   0   6  24  24  24   6   0   0  96  96   0  96   0   6
T |  96   6  96   0   0  89   0   0   9  24  24  24  71   0   0   0   0  96   0  96   6

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Dendrogram of similar interfaces ?

matrix format

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updated Mon Dec 18 12:36:50 2023