interface graph thumbnail
legend  pdf

structure nameACETATE-FREE STRUCTURE OF THE ENZYME-PRODUCT COMPLEX RESULTING FROM TDG ACTION ON A GU MISMATCH
(GT mismatch-specific thymine DNA glycosylase)
referencePozharski et al. 'Nucleic 43 9541 2015
sourceHomo sapiens
experimentX-ray (resolution=1.72, R-factor=0.200)
structural superfamilyUracil-DNA glycosylase-like;
sequence familyUracil DNA glycosylase superfamily;
multimeric complexes2rba_AB 3ufj_AB 3uo7_AB 3uob_AB
reference complex4z47_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHHSKARCAQP

Estimated binding specificities ?

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# IC=5.766 IC/col=0.721 n_of_columns=8 specificity:   
A |   0  13  24  96  24   0   0  54
C |  96  13  24   0  24   0   0  16
G |   0  16  24   0  24  96   0  13
T |   0  54  24   0  24   0  96  13
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updated Mon Dec 18 11:44:42 2023