4xqk_AB : 3D-footprint complex

structure name	ATP-DEPENDENT TYPE ISP RESTRICTION-MODIFICATION ENZYME LLABIII BOUND TO DNA
reference	Saikrishnan et al. Nat.Chem.Biol. 11 870 2015
source	LACTOCOCCUS LACTIS SUBSP. CREMORIS
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;P-loop containing nucleoside triphosphate hydrolases;Restriction endonuclease-like;
reference complex	4xqk_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4xqk_A interface=350,807,958,960,961,964,966,995,996,998,1058,1059,1063,1074,1076,1077,1171,1218,1258,1259,1261,1300, kqtfddlinqintgtlfekltlaylkneptykalyqnvwllsevpesygipvdlvaeqkngdlvaiqakfytnkvgkseinsfvaelgksyyqrglivstmddwnsnaretidqnekgieiiglsdlrnsqidwsqfnferpenvvvkkpkklrdyqqtakenalahfkendrgqlimapgtgktftslkisealskdkdgpfkvlylvpsiqlltqtlrgwnndteltmtsmavtstedikasdigypattsskkilqnwhdfeslpkqtdmlvvfstyqsievigeaqkegfpefdfiisdeahrttgaheaakeasafskvhsnnnvkglkrmyqtatpkiygesaKknakdksillssmddeskygevffrmgfgqavsrdiltdykvmvlavdeaaiqkdmqrtladpenglniddvgrivgiwngmmrrngykknspydgapleraiaftrtieeskkvssqfeevvneyisihlsmrhadgqmnalqkgevldwlanpnkpadearivsnvrfltegidiptldaviflspkksqvdivqavgrimrkaegkdygyiilpiviptgekpetildnnknyetvwqvinalrsvderfeamidklnmakpkqlkvigvgsspdtelefewdkfegaifgkivqkvgdrkylenwskdvakiaerqinwiknklsdkkdpislefkkfvsslqhnindsidekqaaemlsqhlitkpifealfseysfvnqnpvsqamesivselekagfakeqenleplyesvrmraegiekaedkqkiivtlydkffktafkatterlgiVftpievvdfivhsvddvlkkhfgkslaskdvhildpftgtgtfivrtltylkeqmdageisladitrkfmkelhaneivllsyyiaainiestfdeingdeegyvpfegivltdtfestetedtldddyfgtnderlkrqqkvpitvimgNpPYsaKqKnedgnqirttyekldaslqnswvetstaTNkNnlfdsyiramrwssdrisdngvigfitnnsfidgnamdgmrqslleefsdiyvlnlkggIRgktKdqsaleggniFdIMtgvtiimlikksdytvegrihyldignnldkyqkleklknwkslngatsefqniipnekgdwinqrnsnfdelislgnkkgsdslfidytgglKtgrdnwswnfskeqvelsmkssidyynqylgdtniykedvpdiswtRslkqrferretqswqgermylgmyrpftkkhvyyaqawiDRqYqmtkvlpsstssnlmislsnktggkqfstlivdvlpdvNlftggsqnlpkylyrnndtgnlfdnsekysairhevlnklpnlseedamyyvyglfhsiqygkvyyedlaksfpkipnvkhkekyikigkeladlhlnyenqpicegidvqiselnyrvkkmkhpkkgvldtiiynesitiknipekayeyvvngrpaiewiinqyqvktdkksgitddpnefsddpkyilnlllsvitvsmrtlelidelpefeiq > 4xqk_B interface= qtfddlinqigtlfekltlaylkneptykalyqnvwllsevdlvaeqkngdlvaiqakfytnkkseinsfvaelgksyyqrglivstmddwnsnaretieiiglsdlrnsqidwsqfnfpenvvvkkpkklrdyqqtakenalahfkendrgqlimapgtgktftslkisealskdkdgpfkvlylvpsiqlltqtlrgwnndteltmtsmavttedikasdigypattsskkilqnwhdfeslpkqtdmlvvfstyqsievigeaqkegfpefdfiisdeahrttgaheaakeasafskvhsnnnvkglkrmyqtatpkiygesakknakdksillssmddeskygevFfrmgfgqavsrdiltdykvmvlavdeaaiqkdmqrtladpenglniddvgrivgiwngmmrrngypydgapleraiaftrtieeskkvssqfeevvnesihlsmrhadgqmnalqkgevldwlanpnkpadearivsnvrfltegidiptldaviflspkksqvdivqavgrimrkaegkdygyiilpiviptgekpetildnnknyetvwqvinalrsvderfeamidklnmakpkqlkvigvgsstelefewdkfegaifgkivqkvgdrkylenwskdvakiaerqinwiknklsdkkdpislefkkfvsslqhnindsidekqaaemlsqhlitkpifealfseysfvnqnpvsqamesivselekagfakeqenleplyesvrmraegiekaedkqkiivtlydkffktafkatterlgivftpievvdfivhsvddvlkkhfgkslaskdVhildpftgtgtfivrtltylkeqmdageisladitrkfmkelhaneivllsyyiaainiestfdeingdeegyvpfegivltdtfestetedtldddyfgtnderlkrqqkvpitvimgnppysakqknedgnqirttyekldaslqnswVeTStaTnKnnlfdsyiramrwssdrisdngvigfitNNsFidgnamdgmrqslleefsdiyvlnlkggirgktkdqsaleggnifdimtgvtiimlikkSDytvEgrihyldignNlDKyqkleklknwkslngatsefqniipnekgdwinqrnsnfdelislgnkkgsdslfidytgglktgrdnwswnfskeqvelsmkssidyynqylGdtniykedvpdiswtrslkqrferretqswqgermylgmyrpftkkHvyyaqawidrqyqmtkvlpsstssnlmislsnktggkqfSTlIvdvlpdvnlftggsqnlpkylyrnndtgnlnsekysaiRhevlnklpnlseedamyyvyglfhsiqygkvyyedlaksfpkipnvkhkekyikigkeladlhlnyenqpicegidvqiselnyrvkkmkhpkkgvldtiiynesitiknipekayeyvvngrpaiewiinqyqvktdkksgitddpnefsddpkyilnlllsvitvsmrtlelidelpefeiq
interface signature	KVNPYKKTNNIRKFIMKRDRYN/FVVTSTKNNFSDENDKGHSTIR

Estimated binding specificities ?

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# IC=10.998 IC/col=0.550 n_of_columns=20

specificity:

A |  12  21  24  24  24  24  24  24  24  24  24  24   0   0   0  96   0   0   0   0
C |  53  10  24  24  24  24  24  24  24  24  24  24  96   0   0   0   0  96  96   0
G |  10  23  24  24  24  24  24  24  24  24  24  24   0   0  96   0  96   0   0  96
T |  21  42  24  24  24  24  24  24  24  24  24  24   0  96   0   0   0   0   0   0

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updated Fri Dec 15 21:30:32 2023