interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) Q369P ZINC FINGERS IN COMPLEX WITH METHYLATED DNA
(Wilms tumor protein, isoform 4CRA_a)
referenceOlanrewaju et al. 'Genes 28 2304 2014
sourceHomo sapiens
experimentX-ray (resolution=2.49, R-factor=0.210)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDRRDHTRDER

Estimated binding specificities ?

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# IC=7.621 IC/col=0.762 n_of_columns=10 specificity:   
A |  56  24  24   4   0   0  96   7   0   9
C |  13  24  24  88  96  96   0  74   0  69
G |  13  24  24   2   0   0   0   7  96   9
T |  14  24  24   2   0   0   0   8   0   9
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updated Mon Dec 18 11:14:30 2023