4pzi_A : 3D-footprint complex

structure name	ZINC FINGER REGION OF MLL2 IN COMPLEX WITH CPG DNA (HISTONE-LYSINE N-METHYLTRANSFERASE 2B)
reference	Structural Genomics Consortium (SGC)
source	HOMO SAPIENS
experiment	X-ray (resolution=2.15, R-factor=0.228)
sequence family	CXXC zinc finger domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4pzi_A interface=7,42,43, hhgkkmRmarcghcrgclrvqdcgscvncldkpkfggpntkKQccvyrkcdkiearkmerl
interface signature	RKQ

Estimated binding specificities ?

readout + contact

# IC=3.303 IC/col=0.826 n_of_columns=4

specificity:

A |  41   0   0   2
C |  20  95  87   5
G |  20   1   3  87
T |  15   0   6   2

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RC------KGQG------   L         +-----4pzi_A    
                             +-----2 
  ----------RGQG--MTRT   L   !     +-----5w9q_B    
                           --3 
  --------KTKGQC------   L   !           +4nw3_A    
                             +-----------1 
  RC--NTICKGKGQGKT----   L               +2kkf_A

home
updated Mon Dec 18 11:10:09 2023