4nca_A : 3D-footprint complex

structure name	STRUCTURE OF THERMUS THERMOPHILUS ARGONAUTE BOUND TO GUIDE DNA 19-MER AND TARGET DNA IN THE PRESENCE OF MN2+
reference	Sheng et al. Proc.Natl.Acad.Sci.USA 111 652 2014
experiment	X-ray (resolution=2.49, R-factor=0.203)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 502;
multimeric complexes	3hk2_AB 3hvr_AB
reference complex	4ncb_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4nca_A interface=41,42,45,57,79,265,278,443,444,447,484,608,609,645, hlgktevflnrfalrplnpeelrpwrlevvldpppgreevYPllAqvarraggvtvRmgdglaswsppevlvlegtlaRmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrvawvadpkdprkpiphltgllvpvltLedlheeegslalSlpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllreglpsqilnvplreeerHRweNallgllakaglqvvalsgaypaelavgfdaggresfRfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdFRgtprplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	YPARRLSHRNRFRF

Estimated binding specificities ?

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# IC=4.042 IC/col=0.269 n_of_columns=15

specificity:

A |   0  42  12  24   0  42  24  24  24  24  24  24  24  24   0
C |   0  20  12  24   0  20  24  24  24  24  24  24  24  24   0
G |  96  16  58  24  14  16  24  24  24  24  24  24  24  24   0
T |   0  18  14  24  82  18  24  24  24  24  24  24  24  24  96

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updated Mon Dec 18 11:00:09 2023