| structure name | STRUCTURE OF THERMUS THERMOPHILUS ARGONAUTE BOUND TO GUIDE DNA AND 19- MER TARGET DNA WITH MG2+ (ARGONAUTE) |
| reference | Sheng et al. Proc.Natl.Acad.Sci.USA 111 652 2014 |
| source | THERMUS THERMOPHILUS |
| experiment | X-ray (resolution=2.19, R-factor=0.178) |
| structural superfamily | Ribonuclease H-like; |
| sequence family | Piwi domain 502; |
| multimeric complexes | 3hk2_AB 3hvr_AB |
| redundant complexes |  3dlh_A
3f73_B
3hjf_A
3hk2_B
3hm9_A
3ho1_A
3hvr_B
3hxm_A
4kpy_B
4n41_A
4n47_A
4n76_B
4nca_A
5gq9_B
5xou_A
5xow_A
5xp8_A
5xpa_A
5xpg_A
5xq2_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | YPARLHRNRFRRF |
Estimated binding specificities ?
| contact |  |
A | 96 24 24 60 24 24 24 24 24 12 96 0 6 12 0 C | 0 24 24 12 24 24 24 24 24 12 0 96 84 18 96 G | 0 24 24 12 24 24 24 24 24 12 0 0 6 12 0 T | 0 24 24 12 24 24 24 24 24 60 0 0 0 54 0scan! |
Dendrogram of similar interfaces ?
matrix format--------YTPAAA--RT------LA--------------PTMT--WT--RT----IT--NT--------HCRG--NG----------RA--------DGVGRGFCRG--RTRGFCAGFG---- L +-------4ncb_B +----1 NA--HTQA------YT----NATGRAKT----KTQT--------NC----------------------LTYTYGHTNG------EG------RANT--------------------KA------ L ! +-------6qzk_A +---3 ------------------KG----TT----------------------------------------KC--FC----------------------------------FALG----YCTC------ L ! ! +------------5ux0_A +---------4 +-2 --PC------------WG------KG--YAWC----------------------------------SA------------RT----RC--------DCRA------------SA--LAPA---- L ! ! +------------6d92_F ! ! --------------------------------------------------------NT------------------------------------------------------------------ +-6 +----------------5g5t_A ! ! --------------------------------------LT--YT--TT--YTYT----RT--IT--NA--FAYTDANT---------------------------------------------- ! ! +----------------------2w42_A +-7 +---5 ----------------------------------------------------------------------------------------QI------LI----------------------QGKG ! ! +----------------------2w36_A --8 ! ------------------------------------------------------------------------------NT--RG------FT-------------------------------- L ! +----------------------------2qkb_A ! ------------------------------------KC--FG------SC----YC--NC----KT---------------------------------------------------------- L +-----------------------------6p7b_B |
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updated Tue Dec 19 09:08:59 2023