4i7y_H : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH A 27-MER APTAMER BOUND TO EXOSITE II (PROTHROMBIN)
reference	Russo Krauss et al.
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=0.184)
structural superfamily	Trypsin-like serine proteases;
sequence family	Trypsin;
multimeric complexes	1hap_HL 1hut_HL 4dih_HL 4dii_HL 4lz4_CD 6evv_HL 6gn7_HL 7zkl_HL
reference complex	6z8v_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4i7y_H interface=85,88,89,91,98,130,159,162,165,175,178,234,237,241,245,249, ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiYihPRyNwrenldRdialmklkkpvafsdyihpvclpdretaaslLqagykgrvtgwgnlkegqpsvlqvvnlpIveRpvCkdstriritDnmFcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfytHvfRlkkWiqkVidqFg
interface signature	YPRNRLIRCDFHRWVF

Estimated binding specificities ?

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# IC=9.337 IC/col=0.549 n_of_columns=17

specificity:

A |   9   0  24  24  24  24  24  24  24  24   0   0   0   0   9   9   0
C |  11   0  24  24  24  24  24  24  24  24   0   0   0   0   9   9   0
G |  67   0  24  24  24  24  24  24  24  24   0   0  96  96  67  69   0
T |   9  96  24  24  24  24  24  24  24  24  96  96   0   0  11   9  96

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updated Mon Dec 18 10:30:07 2023