4a12_ABCD : 3D-footprint complex

structure name	STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH DNA OPERATOR
reference	Buschiazzo et al. 'Plos 9 3108 2013
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=3.15, R-factor=?)
structural superfamily	Thioesterase/thiol ester dehydrase-isomerase;"Winged helix" DNA-binding domain;
reference complex	4a12_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4a12_A interface=35,36,38,39,50, klkkdkrreairqqidsnpfitdhelsdlfqvsiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_B interface=36,38,39,41,42,53, etlklkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_C interface=36,38,39,41,42,53, etlklkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_D interface=33,35,36,38,39,50, klkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr
interface signature	QTRLR/SQTRLR/SQTRLR/SQTRLR

Estimated binding specificities ?

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# IC=20.355 IC/col=0.754 n_of_columns=27

specificity:

A |  94   7  24  24  80   1   0  88  24   1  24   0   0  96  73  24  24  24   5   0  80   3   1  24  96   1  96
C |   0   5  24  24   7  63   0   0  24   3  24   0   0   0   0  24  24  24  86   0  13   0   8  24   0   0   0
G |   2   2  24  24   1  19   0   5  24   2  24   0   0   0  23  24  24  24   4   0   1  90   5  24   0   1   0
T |   0  82  24  24   8  13  96   3  24  90  24  96  96   0   0  24  24  24   1  96   2   3  82  24   0  94   0

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updated Fri Dec 15 18:21:29 2023