3wu1_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ETS1-RUNX1-DNA TERNARY COMPLEX (RUNT-RELATED TRANSCRIPTION FACTOR 1)
reference	Tahirov et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS
experiment	X-ray (resolution=2.40, R-factor=0.213)
structural superfamily	p53-like transcription factors;
sequence family	Runt domain;
multimeric complexes	3wu1_AB
redundant complexes	1h9d_C 1hjc_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wu1_A interface=26,88,116,117,120,123, ladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepR
interface signature	RRVDRR

Estimated binding specificities ?

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# IC=7.514 IC/col=0.939 n_of_columns=8

specificity:

A |  73  81  59   0   0  96   0  66
C |   7   0  14  96  96   0  96  16
G |   7   1  14   0   0   0   0   7
T |   9  14   9   0   0   0   0   7

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGRTVCDCRG   L                         +4l0y_A    
                                       +-1 
  RGRTVCDCRG   L       +---------------2 +3wu1_A    
                       !               ! 
  RGRAVCDCRT   L   +---3               +-6vg8_D    
                   !   ! 
  --------RG     --4   +-----------------7b4n_A    
                   ! 
  ----ATCTRG       +---------------------3qyn_C

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updated Thu Dec 22 19:51:00 2022