| structure name | CRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1, RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA (PROTEIN C-ETS-1) |
| reference | Shiina et al. J.Mol.Biol. 427 1655 2015 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=2.35, R-factor=0.249) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 1mdm_AB 2nny_AB 3mfk_AB 3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC |
| redundant complexes | 1mdm_B
 2nny_A
3mfk_A
3ri4_D
3wtt_H
3wtu_C
3wtw_C
3wtx_C
3wtv
3wty
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | KRRY |
Estimated binding specificities ?
| contact |  |
A | 13 0 0 13 C | 13 96 96 13 G | 13 0 0 16 T | 57 0 0 54scan! |
Dendrogram of similar interfaces ?
matrix format------------KT--RG--RGYA------ L +--3wts_C +-------------2 ------------KT--RG--RGYA------ L ! +--4lg0_B +-8 SG--------DCKT--RG--RGYA------ L ! ! +----3zp5_A ! +-----------3 ----------------TT--CT--NGKG-- L +-9 +----7oot_B ! ! ------------KT--RGATRGYA------ L ! ! +---------4iri_A ! +-------5 --NC------------TT--CT--NGKG-- L +-10 +---------7rh2_B ! ! ------------KT--RGATRGYT------ L ! ! +------1awc_A ! ! +---4 ----------DCKT--RGSTRGYA------ L ! +-------6 +------4bnc_A +-----11 ! ------------------NTCT--NGST-- L ! ! +----------1if1_B ! ! ----------DCKT--RGATRCYA------ L ! ! +5e8i_D +-12 ! +-----------1 ----------DCKT--RG--RGYA----KA L ! ! +------7 +5jvt_A ! ! ! ----RC------------------------ +-13 ! +-----------7cow_T ! ! ! ------------KT--RG--RAYA------ L ! ! +-------------------------6vge_A -14 ! ----------KG----ATNTCT----SC-- L ! +----------------------------2irf_L ! ------NGHTETKGRGQG--QT-------- L +----------------------------4esj_A |
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updated Thu Dec 22 19:50:52 2022