1mdm_AB : 3D-footprint complex

structure name	INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA
reference	Wolberger et al. J.Biol.Chem. 277 45529 2002
source	HOMO SAPIENS / MUS MUSCULUS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Homeodomain-like;"Winged helix" DNA-binding domain;
reference complex	1k78_A 4l18_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1mdm_A interface=11,43,44,48,49,65,68,113,115,116,118,119, gvnqlggvfvNgrplpdvvrqrivelahqgvrpcdisrqlrvSHgcvSKilgryyetgsikpgvIggSkpkvatpkvvekiaeykrqnptmfaweirdrllaervcdndtvpSvSSiNRiirtk > 1mdm_B interface=79,80,83,86,87, rdradlnkdkpvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkp
interface signature	NSHSKISSSSNR/EKRRY

Estimated binding specificities ?

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# IC=11.160 IC/col=0.587 n_of_columns=19

specificity:

A |   5   0   0  96   0  85  24  24  24   0  24  24  24  24  10  24   6  10   5
C |  91   0   0   0   0   0  24  24  24  10  24  24  24  24  69  24   0  10   1
G |   0  96  96   0  96   6  24  24  24  80  24  24  24  24  10  24   5  69  90
T |   0   0   0   0   0   5  24  24  24   6  24  24  24  24   7  24  85   7   0

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updated Fri Dec 15 09:45:59 2023