3ufj_B : 3D-footprint complex

structure name	HUMAN THYMINE DNA GLYCOSYLASE BOUND TO SUBSTRATE ANALOG 2'-FLUORO-2'- DEOXYURIDINE (GT mismatch-specific thymine DNA glycosylase)
reference	Pozharski et al. Proc.Natl.Acad.Sci.USA 109 8091 2012
source	Homo sapiens
experiment	X-ray (resolution=2.97, R-factor=0.265)
structural superfamily	Uracil-DNA glycosylase-like;
sequence family	Uracil DNA glycosylase superfamily;
multimeric complexes	2rba_AB 3ufj_AB 3uo7_AB 3uob_AB
reference complex	4z47_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3ufj_B interface=111,152,153,155,158, tlpdiltfnldiviiginpglmaaykghhypgpgnhfwkclfmsglsevqlnhmddhtlpgkygigftnmverttpgskdlsskefreggrilvqklqkyqpriavfngkCiyeifskevfgvkvknlefglqphkipdtetlcyvmpsssARcAqfPraqdkvhyyiklkdlrdqlkgier
interface signature	CARAP

Estimated binding specificities ?

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# IC=6.008 IC/col=0.207 n_of_columns=29

specificity:

A |   4  24  24   0   9  62  24  24  24  24  24  24  24  24  24  24  24  24  24  96   7  24  24  24  24  24  24  24   4
C |   4  24  24   0  69  11  24  24  24  24  24  24  24  24  24  24  24  24  24   0   4  24  24  24  24  24  24  24  84
G |   4  24  24  96   9  19  24  24  24  24  24  24  24  24  24  24  24  24  24   0  81  24  24  24  24  24  24  24   4
T |  84  24  24   0   9   4  24  24  24  24  24  24  24  24  24  24  24  24  24   0   4  24  24  24  24  24  24  24   4

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updated Mon Dec 18 09:20:14 2023