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structure nameSMALLPOX VIRUS TOPOISOMERASE-DNA TRANSITION STATE
(DNA topoisomerase 1)
referenceVan Duyne et al. Structure 18 127 2010
sourceVariola virus
experimentX-ray (resolution=2.10, R-factor=0.180)
structural superfamilyDNA breaking-rejoining enzymes;DNA topoisomerase I domain;
sequence familyEukaryotic DNA topoisomerase I, catal; Viral DNA topoisomerase I, Nterminal;
reference complex2h7g_X
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQYYRKKYKDERYTSIR

Estimated binding specificities ?

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# IC=12.054 IC/col=1.004 n_of_columns=12 specificity:   
A |   0   0  15   4  82   1   0   0   0   0  24   0
C |   0   0  13  59   1  91  96  96   0   5   9   0
G |   0  96  18  20  13   0   0   0   0   0  59   0
T |  96   0  50  13   0   4   0   0  96  91   4  96
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updated Mon Dec 18 08:07:23 2023