2qby_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HETERODIMER OF CDC6/ORC1 INITIATORS BOUND TO ORIGIN DNA (FROM S. SOLFATARICUS) (CELL DIVISION CONTROL PROTEIN 6 HOMOLOG 3)
reference	Cunningham Dueber et al. Science 317 1210 2007
source	SULFOLOBUS SOLFATARICUS
experiment	X-ray (resolution=3.35, R-factor=0.226)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	CDC6, C terminal;
multimeric complexes	2qby_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2qby_B interface=313,315,336,339,343, knpkvfidplsvfkeipfredilrdaaiairyfvknevkfsnlflgltgtgktfvskyifneieevkkedeeykdvkqayvncrevggtpqavlsslagkltgfsvpkhginlgeyidkikngtrniraiiyldevdtlvkrrggdivlyqllrsdanisvimisndinvrdymeprvlsslgpsvifkpydaeqlkfilskyaeyglikgtyddeilsyiaaisakehgdarkavnllfraaqlasgggiirkehvdkaivdyeqerlieavkalpfhyklalrsliesedvmsahkmytdlcnkfkqkplSyRrfsdiiseldmfgivkiriiNrgRaggVkkyalvedkekvlralnetfedsis
interface signature	SRNRV

Estimated binding specificities ?

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# IC=4.901 IC/col=0.613 n_of_columns=8

specificity:

A |  77  24   0  19  24  24   0   0
C |  19  24  96  19  24  24   0   0
G |   0  24   0  38  24  24  96  96
T |   0  24   0  20  24  24   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------------------ST--RG----------------NGRA----VG----   L                                         +--2qby_B    
                                                                                    +----------------1 
  --TG--------------TT--RGRT--------------SGRT--KT------   L                        !                +--2v1u_A    
                                                                                +---3 
  ------SA----------------------------------------------   L                    !   !       +-----------2qby_A    
                                                                             +--5   +-------2 
  ----------RA------------------------------------------                     !  !           +-----------7jgs_A    
                                                                           +-6  ! 
  TTRA--------------------------------------------------                   ! !  +-----------------------7jps_B    
                                                                         +-7 ! 
  ----------------TT----KATTQTTGLTRT----KA----------FTYT   L             ! ! +--------------------------2p7c_B    
                                                                         ! ! 
  ------------------NT--TCTA----------------------RT----   L           +-8 +----------------------------5zux_A    
                                                                       ! ! 
  ----KA------------------------------------------------               ! !    +-----------------------3r8f_C    
                                                                     +-9 +----4 
  --------NT--------------------------------------------             ! !      +-----------------------5vvr_M    
                                                                  +-10 ! 
  --------------LT--NTHGTA--YTRG--------------KGQA------          !  ! +-----------------------------2efw_A    
                                                               +-11  !  
  ------------------------------HT--ST------------------   L   !  !  +-----------------------------6akp_C    
                                                             -12  !  
  ------------IA----------------------------------------       !  +-----------------------------6ro4_B    
                                                               !  
  --------------------------RTVAITNA--MCRG--------------   L   +-----------------------------1akh_A

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updated Tue Dec 19 06:53:11 2023