interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A HETERODIMER OF CDC6/ORC1 INITIATORS BOUND TO ORIGIN DNA (FROM S. SOLFATARICUS)
(CELL DIVISION CONTROL PROTEIN 6 HOMOLOG 1)
referenceCunningham Dueber et al. Science 317 1210 2007
sourceSULFOLOBUS SOLFATARICUS
experimentX-ray (resolution=3.35, R-factor=0.226)
structural superfamilyP-loop containing nucleoside triphosphate hydrolases;"Winged helix" DNA-binding domain;
sequence familyCDC6, C terminal; ATPase family associated with various cellul;
multimeric complexes2qby_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSTRSRK

Estimated binding specificities ?

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# IC=2.046 IC/col=0.292 n_of_columns=7 specificity:   
A |  38  24  24   0  12  60  38
C |  19  24  24   0  12  12  19
G |  20  24  24   0  60  12  20
T |  19  24  24  96  12  12  19
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----SA------TTRG--ST----------------RTKT----   L                                     +2qby_A    
                                                                   +-------------------1 
  TG----------TTRGRT----------------SG--KT----   L            +----4                   +2v1u_A    
                                                              !    ! 
  ------RA------------------------------------             +--6    +--------------------7jgs_A    
                                                           !  ! 
  TTRA----------------------------------------             !  +-------------------------7jps_B    
                                                           ! 
  ----------TT--KATTQTTG--LTRT----KA----FT--YT   L       +-7          +-----------------2p7c_B    
                                                         ! !     +----3 
  ------------------------YG------------------           ! !     !    !             +---4lb5_B    
                                                         ! +-----5    +-------------2 
  --------------------NASTHT--STLT------------   L     +-8       !                  +---7cby_C    
                                                       ! !       ! 
  --------------------NA--HT--STLT------------   L     ! !       +----------------------2a07_J    
                                                     +-9 ! 
  --------QT----------------------------------       ! ! +-----------------------------6m6b_M    
                                                   -10 ! 
  --------------------IT--QCNA--ACRG----------   L   ! +-----------------------------6a8r_A    
                                                     !  
  ------------NTTC--TA--------------------RT--   L   +-----------------------------5zux_A    
                                                   

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updated Tue Dec 19 06:52:47 2023