interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
(Iron-dependent repressor ideR)
referenceWisedchaisri et al. Biochemistry 46 436 2007
sourceMycobacterium tuberculosis
experimentX-ray (resolution=2.40, R-factor=0.201)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, metal bindin; Iron dependent repressor, Nterminal D; MarR family;
multimeric complexes2isz_ABCD 2it0_ABCD
redundant complexes2it0_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQRR

Estimated binding specificities ?

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# IC=4.841 IC/col=0.807 n_of_columns=6 specificity:   
A |   9   9  75   6   0   0
C |   6   6   6   6   0   6
G |   6   6   6  75  96  89
T |  75  75   9   9   0   1
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------ST--PTTC--QG--RG------   L                           +1f5t_A    
                                                  +----------------1 
  RGRTKG------------------------YGKC   L          !                +6lui_A    
                                                +-5 
  ------------------------YG--------            ! !                +2heo_D    
                                                ! !     +----------2 
  ------LT------RTSGTGQTRG----------   L      +-6 +-----3          +2xro_E    
                                              ! !       ! 
  ----------------TTHT--KG----RC----   L      ! !       +----------7b0c_A    
                                           +--7 ! 
  --------TC--STKTPTTTFT------------       !  ! +-----------------4ass_H    
                                           !  ! 
  ------------ST--PTTCSTQC--RA------   L --8  !   +--------------1ddn_B    
                                           !  +---4 
  ------------DCLT--AGTTRG--RG------   L   !      +--------------5h3r_A    
                                           ! 
  --------SGQG--YCNC----------------       +---------------------2ve9_C    
                                         

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updated Tue Dec 19 06:38:05 2023