interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF ACTIVATED NOTCH, CSL AND MAML ON HES-1 PROMOTER DNA SEQUENCE
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF...)
referenceBlacklow et al. 'Cell(Cambridge,Mass.)' 124 973 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=3.25, R-factor=0.241)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

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# IC=7.379 IC/col=0.922 n_of_columns=8 specificity:   
A |   5   5   0   5   5   5  96  91
C |   5   5   0   6  10   6   0   5
G |   6  80   0  85  66  80   0   0
T |  80   6  96   0  15   5   0   0
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updated Mon Dec 18 06:43:21 2023