3nbn_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A DIMER OF NOTCH TRANSCRIPTION COMPLEX TRIMERS ON HES1 DNA
reference	Blacklow et al. Nat.Struct.Mol.Biol. 17 1312 2010
source	HOMO SAPIENS
experiment	X-ray (resolution=3.45, R-factor=?)
structural superfamily	DNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
reference complex	3iag_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3nbn_A interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep > 3nbn_D interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep
interface signature	YERSKKSQ/YERSKKSQ

Estimated binding specificities ?

readout + contact

# IC=13.235 IC/col=0.441 n_of_columns=30

specificity:

A |   1   1  24   0  96  68  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0   0   4   0  96  24  82   9
C |   0   0  24   0   0  15  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0  96  77  96   0  24   4  10
G |   4  91  24  96   0   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   9   0   0  24   6  68
T |  91   4  24   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  74  96   0   6   0   0  24   4   9

scan!

home
updated Fri Dec 15 16:13:59 2023