interface graph thumbnail
legend  pdf

structure nameMUTM CROSSLINKED TO UNDAMAGED DNA SAMPLING A:T BASE PAIR IC2
(formamidopyrimidine-DNA glycosidase)
referenceVerdine et al. Science 311 1153 2006
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=2.00, R-factor=0.205)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyFormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2; Zinc finger found in FPG and IleRS;
reference complex3u6p_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRRFR

Estimated binding specificities ?

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# IC=3.125 IC/col=0.781 n_of_columns=4 specificity:   
A |  12  49  96   0
C |  60  15   0   0
G |  12  17   0  96
T |  12  15   0   0
scan!

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updated Mon Dec 18 06:42:54 2023