1hlz_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hlz_A interface=22,25,29,30,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrfgRip > 1hlz_B interface=24,27,31,32,79,81, gmvllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgR
interface signature	EKRRR/EKRRFR

Estimated binding specificities ?

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# IC=15.697 IC/col=0.872 n_of_columns=18

specificity:

A |  73  96  20  24  11   0   0   2   0  96  22  24  24   0   0  11   0  93
C |  13   0  53  24   1   0   0   0  96   0  49  24  24   0   0   3  96   0
G |   8   0  21  24   2  96  96   3   0   0  17  24  24  96  96   2   0   1
T |   2   0   2  24  82   0   0  91   0   0   8  24  24   0   0  80   0   2

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updated Fri Dec 15 09:10:09 2023