1hjb_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER (CCAATENHANCER BINDING PROTEIN BETA)
reference	Tahirov et al.
source	HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=0.244)
structural superfamily	Leucine zipper domain;
sequence family	Basic region leucine zipper; bZIP transcription factor;
multimeric complexes	1hjb_ABC 1hjb_DEF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hjb_A interface=11,14,17,18,21,22, dkhsdeykirRerNniAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkq
interface signature	RNAVSR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |   0   0  13   0  16
C |   0   0  16  96  54
G |   0   0  13   0  13
T |  96  96  54   0  13

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Dendrogram of similar interfaces ?

matrix format

  
  --RANT----AAVT--STRG----------------   L                       +-1hjb_A    
                                                 +---------------3 
  ----NCRT--ATAT--STRG----------------           !               +-1t2k_D    
                                             +---6 
  --------RG----NC----YGAT------RC----   L   !   !                +4eot_A    
                                             !   !         +------1 
  --------RG----NC----YGAT----CTRG----   L   !   +---------5      +2wt7_B    
                                             !             ! 
  ----QC----FTRC----------------------   L --7             +-------7aw7_D    
                                             ! 
  ------------------NT----ATAT----STRG   L   !                    +-1dh3_C    
                                             !                  +-2 
  ----NC----AT----STRA----------------       +------------------4 +-1a02_J    
                                                                ! 
  NCTTAT------RG----------------------   L                      +--2dgc_A

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updated Thu Dec 22 17:35:01 2022