DNA Binding Motif

Accessions: 1mey_CF (3D-footprint 20231221)
Names: CONSENSUS ZINC FINGER
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA
Length: 23
Consensus: GGGGCAGAACnnTGAGGCAGAAC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 6 5 75 10 G
03 0 0 96 0 G
04 0 0 96 0 G
05 0 96 0 0 C
06 96 0 0 0 A
07 0 0 96 0 G
08 96 0 0 0 A
09 96 0 0 0 A
10 0 90 0 6 C
11 24 24 24 24 n
12 24 24 24 24 n
13 5 5 5 81 T
14 6 5 80 5 G
15 70 5 16 5 A
16 0 0 96 0 G
17 0 0 96 0 G
18 1 90 5 0 C
19 96 0 0 0 A
20 0 0 96 0 G
21 96 0 0 0 A
22 96 0 0 0 A
23 0 80 5 11 C
Type: Heterodimer
Binding TFs: 1mey_C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
1mey_F (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 1mey_A
1mey_B
Publications: Kim C.A, Berg J.M. A 2.2 A resolution crystal structure of a designed zinc finger protein bound to DNA. Nature structural biology 3:940-5 (1996). [Pubmed]

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