DNA Binding Motif

Accessions: 5u01_ABCD (3D-footprint 20231221)
Names: Transcription factor p65
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Cooperative DNA binding by two RelA dimers
Length: 23
Consensus: CGGAAnTTCCCGGGAAnTTCCGC
Weblogo:
PSSM: P0 A C G T
01 7 76 7 6 C
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 76 7 6 7 A
06 24 24 24 24 n
07 3 7 10 76 T
08 6 3 3 84 T
09 0 96 0 0 C
10 0 96 0 0 C
11 0 96 0 0 C
12 0 0 96 0 G
13 0 0 96 0 G
14 0 0 96 0 G
15 96 0 0 0 A
16 84 3 3 6 A
17 24 24 24 24 n
18 3 3 6 84 T
19 0 0 0 96 T
20 0 96 0 0 C
21 0 96 0 0 C
22 0 0 96 0 G
23 3 87 3 3 C
Binding TFs: 5u01_A / 5u01_B / 5u01_C / 5u01_D (Rel homology domain (RHD))
Binding Sites: 5u01_E / 5u01_F
Publications: Mulero MC, Huang DB, Nguyen HT, Wang V, Li Y, Biswas T, Ghosh G. DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated. J Biol Chem : (2017). [Pubmed]

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