DNA Binding Motif

Accessions: 6hb4_J (3D-footprint 20231221)
Names: Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TFAM in Complex with Site-Y
Length: 18
Consensus: AATTGAnnnnnnnnACAG
Weblogo:
PSSM: P0 A C G T
01 73 9 7 7 A
02 96 0 0 0 A
03 7 7 7 75 T
04 0 0 0 96 T
05 0 0 96 0 G
06 75 7 7 7 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 24 24 24 24 n
15 96 0 0 0 A
16 0 96 0 0 C
17 96 0 0 0 A
18 9 7 73 7 G
Binding TFs: 6hb4_J (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Cuppari A, Fernández-Millán P, Battistini F, Tarrés-Solé A, Lyonnais S, Iruela G, Ruiz-López E, Enciso Y, Rubio-Cosials A, Prohens R, Pons M, Alfonso C, Tóth K, Rivas G, Orozco M, Solà M. DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res 47:6519-6537 (2019). [Pubmed]

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