DNA Binding Motif

Accessions: 1p47_AB (3D-footprint 20231221)
Names: Early growth response protein 1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of tandem Zif268 molecules complexed to DNA
Length: 20
Consensus: GGCGTGGGCGGCGTGGGCGT
Weblogo:
PSSM: P0 A C G T
01 5 6 80 5 G
02 0 0 96 0 G
03 0 90 1 5 C
04 0 0 96 0 G
05 6 5 5 80 T
06 0 0 96 0 G
07 0 0 96 0 G
08 0 0 96 0 G
09 0 96 0 0 C
10 0 0 96 0 G
11 0 0 96 0 G
12 5 80 5 6 C
13 0 0 96 0 G
14 5 0 6 85 T
15 0 0 96 0 G
16 0 0 96 0 G
17 0 0 96 0 G
18 6 80 5 5 C
19 0 0 96 0 G
20 5 5 6 80 T
Type: Heterodimer
Binding TFs: 1p47_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
1p47_B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 1p47_C
1p47_D
Publications: Peisach E, Pabo C.O. Constraints for zinc finger linker design as inferred from X-ray crystal structure of tandem Zif268-DNA complexes. Journal of molecular biology 330:1-7 (2003). [Pubmed]

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