interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA-DGMPNPP TERNARY MISMATCH COMPLEX IN 0.12 MM MN2+ FOR 600S
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.67, R-factor=0.189)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRF

Estimated binding specificities ?

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# IC=1.441 IC/col=0.240 n_of_columns=6 specificity:   
A |   6  13  24  22  42  10
C |  78  13  24  27  18  10
G |   6  57  24  22  18  10
T |   6  13  24  25  18  66
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updated Tue Dec 19 00:26:02 2023