interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA-DGMPNPP TERNARY MISMATCH COMPLEX IN 1.0 MM MG2+ FOR 600S
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.66, R-factor=0.185)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSLRF

Estimated binding specificities ?

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# IC=2.321 IC/col=0.387 n_of_columns=6 specificity:   
A |  72  12  21  30  12   2
C |   8  12  21  22  60   1
G |   8  12  33  22  12  92
T |   8  60  21  22  12   1
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updated Tue Dec 19 00:25:43 2023