interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 10.0 MM MN2+ FOR 600S
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.67, R-factor=0.180)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSLRF

Estimated binding specificities ?

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# IC=1.604 IC/col=0.267 n_of_columns=6 specificity:   
A |  66  19  24  30  13   4
C |  10  19  24  22  63   4
G |  10  20  24  22  10  81
T |  10  38  24  22  10   7
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updated Tue Dec 19 00:24:40 2023