7tjh_ABCDEI : 3D-footprint complex

structure name	S. CEREVISIAE ORC BOUND TO 84 BP ARS1 DNA AND CDC6 (STATE 1) WITH FLEXIBLE ORC6 N-TERMINAL DOMAIN
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Inhibitor of apoptosis IAP repeat;"Winged helix" DNA-binding domain;
reference complex	5v8f_B 5v8f_C 5v8f_D 5v8f_E 5zr1_A 5zr1_F 7mca_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7tjh_A interface=5,7,12,17, virkFtKknvaRakkkYtpfskrfksiaaipdltslpefygnrfenklkttqkhqivetifskvkkqlnsslparenefasiylsaysaiesdsattiyvagtpgvgktltvrevvkellsssaqreipdflyveinglkmvkptdcyetlwnkvsgerltwaasmeslefyfkrvpknkkktivvlldeldamvtksqdimynffnwttyenakliviavantmdlperqlgnkitsrigftrimftgytheelkniidlrlkglndsffyvdtktgnailivrkvrlrmsadaieiasrkvasvsgdarralkvckraaeiaekhymakhgygydgvqtvhithvmkalnetlnshvitfmtrlsftaklfiyallnlmkkngsqeqelgdivdeikllievngsnkfvmeiaktlfqqgsdniseqlriiswdfvlnqlldagilfkqtmkndriccvklnisveeakramnedetlrnl > 7tjh_B interface=20,21,150, sassfldtfegyfdqrkivRTnaksrhtmsmapdvtreefslvsnffnenfqkrprqklfeiqkkmfpqywfeltqgfsllfygvgskrnfleefaidylspkiaysqlnsipclilngynpscnyrdvfkeitdllvpaeltrsetkyWgnhvilqiqkmidfyknqpldiklilvvhnldgpsirkntfqtmlsflsvirqiaivastdhiyapllwdnmkaqnynfvfhdisnfepstvestfqdvmk > 7tjh_C interface= adaqrshytvypslphipfVKllsgkesevnvekrwelyhqlhshfhdqvdhiidnieadlkaeisdllysrcfntifllgsdsttkielkdessrynvlieltpkespnvrmmlrrsmyklysaadaeendvsydlslvenfkrlfgkDlamvfnfkdvdsinfntldnfiillksafkydhvkislifnintnlsnieknlrqstirllkrnyhkldvssnkgfkygnqifqsfldtvdgklnlsdrfvefilskmanntnhnlqlltkmldyslmsyffqnafsvfidpvnvdflnddylkilsrcptfmffveglikqnrgleeffveflvrenpinghakfvarfleeelnitnfnlielyhnlligkldsyldrwsackeykdrlhfepidtifqelftldnrsglltqsifpsyksniednllsweqvlpslsgdldkimapvlgqlfklyreanmtiniydfyiafretlpkeeilnfirkdpsntkllelaetpdafdkvalilfmqaifafenmglikfqstksydlvekcvwrgi > 7tjh_D interface=390,391,394,395, dpgfgslqrrllqqlygtlptdekiiftylqdcqqeidriikqsiiqkeshsvilvgprqsyktylldyelsllqqsykeqfitirlngfihseqtaingiatqleqqlqkihtissgsltevfekillllditkitvvfifdeidtfagpvrqtllynlfdmvehsrvpvcifgcttklnileylekrvksrfsqrviympqiqnlddmvdavrnlltvrseispwvsqwnetlekelsdprsnlnrhirmnfetfrslptlknsiiplvatsknfgslctaikscsfldiynknqlsnnltgrlqslsdlelailisaarvalrakdgsfnfnlayaeyekmikainsrtiklwlkkdvknvwenlvqldffteksavglrdnataaFYasNYqfqgtmipfdlrsyqmqiilqelrriipksnmyyswtql > 7tjh_E interface=331,334,337, mnvttpevafreyqtnclasyisadpditpsnlilqgysgtgktytlkkyfnanpnlhavwlepvelvswkpllqaiartvqyklktlypnipttdydplqveepfllvktlhnifvqyeslqektclflildgfdslqdldaalfnkyiklnellpkdskinikfiytmletsflqrysthciptvmfprynvdevstilvmsrcgelmedsclrkriieeddqfqnvaanfihlivqafhsytgndifalndlidfkwpkyvsritkenifeplalyksaiklflstddnldlsiiskylliasyicsyleprydasifsrktriiqgRaaYgrRkkkevnprylqpslfaierllaifqaifpialreeslmkanievfqnlselhtlkliattmnknidylspkvrwkvnvpweiikeisesvhfnisdyfsdih > 7tjh_I interface= siflrtkallqksselgalpartaeyeqvmnflakaisehrsdslyitgppgtgktaqldmiirqkflqnlswfelpdgrlesvavtsincislgepssifqkifdsfqdlngptlqiknmqhlqkflepyttfvvvldemdrllhantsetqsvrtilelfllaklptvsfvligmansgllpqtivfqpytaeqmyeiviqkmsslptiifqpmaikfaakkcagntgdlrklfdvlrgsieiyelekkiglnyiakvfskfvnnnstrtriaklniqqklilctiiqslklnsdatidesfdhyikaitktdtlaplqrnefleictIleTcgLvsikktkckgktkrfvdkidvdldmrefydemtkisilkpfl
interface signature	FKRY/RTW/VKD/FYNY/RYR/ITL

Estimated binding specificities ?

readout + contact

# IC=18.311 IC/col=0.610 n_of_columns=30

specificity:

A |   3   0   3  96   0   0   0  24   9  96   1  24  24  24  24  24  24  24  24  24  24  24  24  11   0   1   1   0   1   1
C |   1   0   6   0   0   0   1  24   5   0   0  24  24  24  24  24  24  24  24  24  24  24  24   9   0  90   1   0   6   1
G |   4   0   3   0   0  96   1  24   9   0  95  24  24  24  24  24  24  24  24  24  24  24  24  15   1   4   0   1  38   4
T |  88  96  84   0  96   0  94  24  73   0   0  24  24  24  24  24  24  24  24  24  24  24  24  61  95   1  94  95  51  90

scan!

home
updated Sun Dec 17 12:34:44 2023