7oz2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA SHOWING A TRANSIENT P-POCKET
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=2.85, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	5d3g_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oz2_A interface=62,73,75,95,116,152,158,184,185,266,449,476, vpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvFackkkdstkwRkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpQgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oz2_B interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkKdstkwrklvdFrElnkrtqdfwphpaglkkkkSvtvldvgdayfsvpldedfrKytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkiLepfkkqnpdiviyqymddlyvgsdlEIgqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikVrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwy
interface signature	FRLIYQPYMNRQ/KFESKSLEIV

Estimated binding specificities ?

contact

# IC=5.192 IC/col=0.273 n_of_columns=19

specificity:

A |   0   8   0   8  24  24  24  24  24  24  24  24  24  24  24  24  24   0  11
C |  96   8   0  69  24  24  24  24  24  24  24  24  24  24  24  24  24  87   8
G |   0  72  96   8  24  24  24  24  24  24  24  24  24  24  24  24  24   9   8
T |   0   8   0  11  24  24  24  24  24  24  24  24  24  24  24  24  24   0  69

scan!

home
updated Sun Dec 17 10:01:07 2023