7oxq_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA IN COMPLEX WITH FRAGMENT 048 AT THE TRANSIENT P-POCKET.
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=3.30, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	5d3g_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oxq_A interface=73,75,95,116,152,158,184,185,266,449,476, vpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwRkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpQgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oxq_B interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdFrElnkrtqdfwphpaglkkkkSvtvldvgdayfsvpldedfrKytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkiLepfkkqnpdiviyqymddlyvgsdlEIgqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikVrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	RLIYQPYMNRQ/FESKSLEIV

Estimated binding specificities ?

readout + contact

# IC=2.757 IC/col=0.145 n_of_columns=19

specificity:

A |   0  12  10  13  20  24  22  24  24  24  24  24  24  24  24  21  24  13  19
C |  96  12   8  56  20  24  30  24  24  24  24  24  24  24  24  23  24  57  19
G |   0  60  70  13  36  24  22  24  24  24  24  24  24  24  24  31  24  13  19
T |   0  12   8  14  20  24  22  24  24  24  24  24  24  24  24  21  24  13  39

scan!

home
updated Sun Dec 17 09:59:57 2023