interface graph thumbnail
legend  pdf

structure nameTARGET-BOUND SPCAS9 COMPLEX WITH TRAC FULL RNA GUIDE
(CRISPR-associated endonuclease Cas9Csn1)
referencevan Overbeek et al. Mol.Cell 81 3637 2021
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=2.75, R-factor=0.211)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=2.886 IC/col=0.721 n_of_columns=4 specificity:   
A |   7   0   3  18
C |  74   0   3  18
G |   8  96  85  18
T |   7   0   5  42
scan!

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updated Mon Dec 18 21:54:29 2023