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structure nameZBTB7A ZINC FINGER DOMAIN BOUND TO DNA DUPLEX CONTAINING GGACCC (OLIGO 23)
(Zinc finger and BTB domain-containing protein 7A)
referenceHorton et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=2.24, R-factor=0.192)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7n5v_AB
redundant complexes7n5s_A 7n5t_A 7n5u_A 7n5v_A 8e3d_A 8e3e_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRDK

Estimated binding specificities ?

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# IC=5.582 IC/col=0.930 n_of_columns=6 specificity:   
A |   0   0   0   0  12  60
C |   0   0   0   0  60  12
G |  96  96  96  12  12  12
T |   0   0   0  84  12  12
scan!

Dendrogram of similar interfaces ?

matrix format
  
  QT--AG--KGRGRG--DCKG----   L                +----7n5w_A    
                                 +------------4 
  RGST--YGYC--QC--TGSTRGYT       !            +----4is1_C    
                                 ! 
  NGKT--WTKG------HTHG--RG   L --7                 +1tf3_A    
                                 ! +---------------3 
  --RGSTDAHARGRGSTDCHG--TT   L   ! !               +5kl3_A    
                                 ! ! 
  --QA--TCNA--QAHTTT----QA   L   +-6                 +1g2d_F    
                                   !               +-1 
  --RG--DAQARGRGSTDCHG--TT   L     !    +----------2 +6b0o_A    
                                   !    !          ! 
  --EC--SCKGRGLT--FCNA----   L     +----5          +1ubd_C    
                                        ! 
  --EC--SCKGRG--TCYCKA--RG              +-----------5yeg_A

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updated Tue Dec 19 19:07:11 2023