7mkd_IJLR : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE BOUND TO LAMBDA PR PROMOTER DNA (CLASS 1)
source	ESCHERICHIA COLI
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;
reference complex	3iyd_A 6psq_M 7c97_K
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7mkd_I interface=150,174,181,182,198,199,370,373,469,496,507,513,537,540,541, vysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhRspgvffdsdkgkthssgkvlynaRiipyrgSWldfefdpkdnlfvriDRrrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiyrmmRpgEpptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddidhlgnrrirsvgemaenqfrvglvRveravkerlslgdldtlmpqdminakPisaavkeffgSsqlsqFmdqnnplseithkrrisalgpggLtrERagfevrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginieled > 7mkd_J interface=244,299,411,412,775,776, efdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggRfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgRaitgsnkrplksladmikgkqgrfrqnllgkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnrAPtlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalkTAnsgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltssiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqtgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraa > 7mkd_L interface=12,14,15,18,26,32,246,248,249,259,282,283,286,288,289,291,292,293,295,296,299,300,303,318,321,324,327,368,374,377,380,382,385,446,447,448,449,451,452, ssveseigrttDpVRmyMremgtveLltregEidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvdppelarekaelraqyvvtrdtiktaqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveaNlRLvisiakkytNrglqfldliqegniglmkavdkFEyrRgYKfSTYaTWwiRQaiTrsiadqartiripvHmiEtiNklNrisrqmlqemgreptpeelaermlmpedkirkvlkiakepIsmetpIgdDedShLgdFiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytleevgkqfdvTRERiRQieakalrklrhpsrsevlrsfl > 7mkd_R interface=16, dpillrpvddleltvRsanclkaeaihyigdlvqrtevellktpnlgkkslteikdvlasrglslgmrlenwp
interface signature	RRSWDRRERPSFLER/RRAPTA/DVRMLENRLNFERYKSTYTWRQTHENNIIDSLFTRERRQ/R

Estimated binding specificities ?

contact

# IC=29.655 IC/col=0.674 n_of_columns=44

specificity:

A |   0  96   0   0  24  80  96   0   0  96   0   0  96   0   0  96  15  24  24   6  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  96  96   0  24  24  24   0  50
C |  96   0   0   0  24   5   0  96  96   0   0   0   0   0  96   0  61  24  24  65  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0  96   0   0  96  24  24  24  96  15
G |   0   0   0  96  24   5   0   0   0   0   0   0   0   0   0   0  15  24  24  15  24  24  24  24  24  24  24  24  24  24  24  24  24  96   0   0   0   0   0  24  24  24   0  15
T |   0   0  96   0  24   6   0   0   0   0  96  96   0  96   0   0   5  24  24  10  24  24  24  24  24  24  24  24  24  24  24  24  24   0  96   0   0   0   0  24  24  24   0  16

scan!

home
updated Sun Dec 17 06:45:59 2023