interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POL ETA S113A WITH RA-ENDED PRIMER AND DATP: IN CRYSTALLO REACTION FOR 230 S
(DNA polymerase eta)
referenceGregory et al. Proc.Natl.Acad.Sci.USA 118 ? 2021
sourceHomo sapiens
experimentX-ray (resolution=1.85, R-factor=0.166)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQWIRSWSNPT

Estimated binding specificities ?

contactlogo
# IC=3.568 IC/col=0.892 n_of_columns=4 specificity:   
A |  96   0   4  19
C |   0   0   4  19
G |   0   0   4  20
T |   0  96  84  38
scan!

home
updated Mon Dec 18 20:58:54 2023