7dbm_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE MUTANT Q151M/Y115F/F116Y/M184V:DNA:DGTP TERNARY COMPLEX
reference	Hattori et al. J.Virol. 95 e0240120 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 / HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.43, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	6kdn_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7dbm_C interface=23,60,73,75,77,93,156,182,183,264,474,500, ispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYVddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 7dbm_D interface= ietvpvklkpgmdgpkvkqwplTeekikalveictemekegkiskigpenpyntpvfaiKkkdstkwrklvdFrElNkrtqdfwevqlgiphPaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaiFqssmtkilepfrkqnpdiviyqymdDLyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrGtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIPYVNQY/TKFENPFDLG

Estimated binding specificities ?

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# IC=7.580 IC/col=0.230 n_of_columns=33

specificity:

A |   0   0  24   0  24  24  24  24  24  24  24  24  24  24  24   7  24  24   7  24  24  24  24  24  24  24  24  24  24  24   7   0   9
C |   0  96  24  96  24  24  24  24  24  24  24  24  24  24  24   7  24  24   7  24  24  24  24  24  24  24  24  24  24  24   7   0  73
G |   0   0  24   0  24  24  24  24  24  24  24  24  24  24  24   9  24  24  73  24  24  24  24  24  24  24  24  24  24  24  73  96   7
T |  96   0  24   0  24  24  24  24  24  24  24  24  24  24  24  73  24  24   9  24  24  24  24  24  24  24  24  24  24  24   9   0   7

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updated Sun Dec 17 01:40:44 2023