6wc2_D : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TERNARY MEF2 CHIMERA/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX (MEF2 CHIMERA,MYOCYTE-SPECIFIC ENHANCER FACTOR 2B,MYOCYTE-...)
reference	Chen et al. J.Mol.Biol. 432 5499 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.10, R-factor=0.188)
structural superfamily	SRF-like;
sequence family	SRFtype transcription factor DNAbinding a;
multimeric complexes	6byy_AB 6byy_CD 6bz1_AB 6bz1_CD 6wc2_ABO 6wc2_DM 6wc2_IJN
redundant complexes	6byy_C 6bz1_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6wc2_D interface=2,14,18,22, gRkkiqitrimdeRnrqVtftKrkfglmkkayelsvlcdceialiifnssnklfqyastdmdkvllkyteysephesrtntdiletlkrrehr
interface signature	RRVK

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |  13  54   0   0  96
C |  54  13  96   0   0
G |  13  16   0   0   0
T |  16  13   0  96   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGKA                   +-------------7x1n_C    
             +-----------2 
  RTKA       !           +-------------3p57_C    
           --3 
  RTKA       !                   +-----1n6j_A    
             +-------------------1 
  RTKA                           +-----1egw_B

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updated Fri Dec 23 01:52:21 2022